Prenatal exposure to ambient fine particulate matter and child lung function in the CANDLE cohort.

ABSTRACT:

Background

Ambient fine particulate matter (PM_2.5) exposure adversely impacts child airway health; however, research on prenatal PM_2.5 exposure, and child lung function is limited. We investigated these associations in the ECHO-PATHWAYS Consortium, focusing on the role of exposure timing during different phases of fetal lung development.

Methods

We included 675 children in the CANDLE cohort born between 2007 and 2011 in Memphis, TN, USA. Prenatal exposure to ambient PM_2.5 was estimated using a spatiotemporal model based on maternal residential history and averaged over established prenatal periods of lung development. Forced expiratory volume in the first second (FEV1) and forced vital capacity (FVC) were measured by spirometry at age 8-9 yea

SUBMITTER: Sherris AR 

PROVIDER: S-EPMC11536642 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature