Benzodiazepine use and incident risk of sudden cardiac arrest in patients with cardiovascular diseases.

ABSTRACT:

Background

Benzodiazepines (BZDs) are commonly prescribed as adjunctive drugs for patients with cardiovascular diseases (CVDs), particularly those who experience anxiety or insomnia. However, the relationship between the use of BZDs and incident risk of sudden cardiac arrest (SCA) has not been well investigated. In this study, we aimed to examine the association between the use of BZDs and the incident risk of SCA among patients with CVD.

Method

In this retrospective cohort study, a total of 74,715 eligible patients with new-onset CVD as a primary cause of hospitalization between July 2016 and August 2022 were included from the health information platform in Shenzhen, China. Among them, 61,761 BZD non-initiators were identified and matched to 12,954 BZD initiators by propens

SUBMITTER: Mo C 

PROVIDER: S-EPMC11536653 | biostudies-literature | 2024 Oct-Dec

REPOSITORIES: biostudies-literature