Association between prognostic nutritional index and mortality risk in patients with community-acquired pneumonia: a retrospective study.

ABSTRACT:

Background

The prognostic nutritional index (PNI), reflecting the body's immune-nutritional status, has been established as a correlate of prognosis across various diseases. However, its significance in community-acquired pneumonia (CAP) remains unclear. This study investigated the relationship between PNI and clinical outcomes in CAP patients.

Methods

In this retrospective cohort study, we aimed to evaluate the prognostic value of the PNI in adults with CAP admitted to the ICU. Participants were selected from the Medical Information Mart for Intensive Care IV (MIMIC-IV) database and categorized into quartiles (Q1-Q4) according to their PNI values. We employed Kaplan-Meier survival analysis, multivariate Cox regression, and restricted cubic spline (RCS) models to explore the

SUBMITTER: Wang G 

PROVIDER: S-EPMC11536940 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature