Characterizing the urobiome in geriatric males with chronic indwelling urinary catheters: an exploratory longitudinal study.

ABSTRACT: The impact of chronic indwelling urinary catheters (IUCs) on the composition and stability of the urinary microbiota remains unknown. The primary aim of this study was to describe the urinary microbiomes of geriatric males with chronic IUCs. A secondary aim was to explore clinical catheter-associated urinary tract infection (CAUTI) courses of the participants. Geriatric male patients with chronic IUCs were followed longitudinally. Catheterized urine, catheter tips, and both urethral and periurethral swabs were collected from participants at monthly intervals. Microbes were isolated and identified from each specimen using an enhanced culture method called expanded quantitative urine culture (EQUC) and targeted 16S rRNA gene DNA sequencing. Microbial outcomes were examined both in the absenc

SUBMITTER: Stewart E 

PROVIDER: S-EPMC11536997 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature