Re-updating the taxonomy of Kluyvera genus for a better understanding of CTX-M β-lactamase origin.

ABSTRACT: The taxonomic definitions within the Kluyvera genus are still unclear, as several deposits might belong to misidentified species or genus or genome assemblies comprehend large indeterminate nucleotide zones. In this study, we performed a comparative phylogenomic analysis of Kluyvera chromosomes and other selected Enterobacterales. We also included the genomic analysis of chromosomal bla_CTX-M/KLU from Kluyvera isolates and assigned the plasmid-encoded bla_CTX/M genes. The study allowed us to propose a new Kluyvera genomospecies and to better define Kluyvera genomosp. 5. Two new CTX-M sub-groups could also be suggested. Even if no chromosomal bla_CTX-M/KLU gene can be found in K. intermedia a

SUBMITTER: Rodriguez MM 

PROVIDER: S-EPMC11537003 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature