Plukenetia volubilis leaves as source of anti-Helicobacter pylori agents.

ABSTRACT:

Introduction

Helicobacter pylori infection is a major issue worldwide, with widespread prevalence, combined with its link to gastritis, peptic ulcers, gastric cancer, and mucosa-associated lymphoid tissue (MALT) lymphoma. Meanwhile, effectiveness of current treatment protocols is limited by increasing antibiotic resistance and patient compliance issues due to long regimens and side effects. Plukenetia volubilis, or sacha inchi, is a valuable source of bioactive molecules. However, studies on its antimicrobial activity, especially against H. pylori, are lacking.

Methods

In this study, the anti-H. pylori activity of P. volubilis leaves water extract was explored using in vitro and in silico approaches. High-Performance Liquid Ch

SUBMITTER: Tan A 

PROVIDER: S-EPMC11537943 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature