Neurodevelopmental outcome in children between one and five years after persistent pulmonary hypertension of term and near-term newborns.

ABSTRACT:

Background

Persistent pulmonary hypertension of the newborn (PPHN) is a serious condition that affects 1-2 per 1,000 newborns. Scientific data report the existence of neurological developmental abnormalities between 10 and 30%, but the description of these disorders linked with this situation of cerebral hypoxia and haemodynamic failure remains poorly documented.

Objective

The main goal of this study was to describe the prevalence of neuro-psychomotor developmental disorders in children aged between one and five years old who have been hospitalised at birth in a neonatal intensive care unit for the management of PPHN.

Methods

All of the newborns ≥34 weeks of gestational age (WGA) with PPHN, treated with inhaled nitric oxide in our neonatal intensive care unit between

SUBMITTER: Atlan L 

PROVIDER: S-EPMC11538055 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature