Whole Blood and Blood Component Resuscitation in Trauma: Interaction and Association With Mortality.

ABSTRACT:

Objective

To evaluate the interaction between whole blood (WB) and blood component resuscitation in relation to mortality after trauma.

Background

WB is increasingly available in civilian trauma resuscitation, and it is typically transfused concomitantly with blood components. The interaction between WB and blood component transfusions is unclear.

Methods

Adult patients with trauma with a shock index >1 who received ≥4 combined units of red blood cells and/or WB within 4 hours across 501 U.S. trauma centers were included using the American College of Surgeons Trauma Quality Improvement Program database. The associations between (1) WB resuscitation and mortality, (2) WB to total transfusion volume ratio (WB:TTV) and mortality, and (3) balanced blood component transfus

SUBMITTER: Dorken-Gallastegi A 

PROVIDER: S-EPMC11538373 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature