An ultrasensitive multimodal intracranial pressure biotelemetric system enabled by exceptional point and iontronics.

ABSTRACT: The accurate monitoring of vital physiological parameters, exemplified by heart rate, respiratory rate, and intracranial pressure (ICP), is of paramount importance, particularly for managing severe cranial injuries. Despite the rapid development of implantable ICP sensing systems over the past decades, they still suffer from, for example, wire connection, low sensitivity, poor resolution, and the inability to monitor multiple variables simultaneously. Here, we propose an ultrasensitive multimodal biotelemetric system that amalgamates an iontronic pressure transducer with exceptional point (EP) operation for the monitoring of ICP signals. The proposed system can exhibit extraordinary performance regarding the detection of minuscule ICP fluctuation, demonstrated by the sensitivity of 115.95 

SUBMITTER: Li J 

PROVIDER: S-EPMC11538422 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature