Optimization of Biocatalytic Rhododendrol Production from Biogenic Rhododendrol Glycosides.

ABSTRACT: An enzyme-catalyzed synthesis of rhododendrol, an intermediate in the production of raspberry ketone, was investigated. The approach involves the enzymatic hydrolysis of rhododendrol glycosides into rhododendrol and a glycosidic residue. Rhododendrol glycosides, which are naturally derived from the inner bark of birch trees-a renewable resource-vary considerably in composition depending on the origin of the plants. In this study, mixtures of betuloside and apiosylrhododendrin from natural resources were used in different proportions. An in-depth study was conducted to assess the feasibility of the process. A mathematical model was developed based on studies of the kinetics and operational stability of the enzyme. The model for betuloside hydrolysis catalyzed by β-glucosidase was validated

SUBMITTER: Leakovic E 

PROVIDER: S-EPMC11539071 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature