Unraveling In vivo Potential of Curcumin-loaded Graphene Quantum Dots on Drug Delivery and Release Kinetics Aspects of Cancer Treatment.

ABSTRACT: This study introduces an innovative magnetic-based multifunctional anti-cancer drug carrier aiming to enhance the efficacy of curcumin in cancer therapy. The research investigates the potential of Graphene Quantum Dots (GQDs) as a curcumin drug delivery system for inhibiting in vivo cancer growth. GQDs with a particle diameter below 10 nm were synthesized via hydrothermal and Hummers methods, exhibiting homogeneity and crystalline structure according to AFM and XRD analyses. FTIR analysis confirmed functionalization success, revealing the formation of bonds between GQDs and curcumin. The optical properties of GQDs were assessed using a UV-Vis spectrophotometer and spectrofluorometer, resulting in vigorous fluorescence with a quantum yield of 1.32%. Subsequently, loading curcumin ont

SUBMITTER: Fahmi MZ 

PROVIDER: S-EPMC11539179 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature