A comparison of male and female renal pelvis urobiome of unilateral stone formers using 2bRAD-M.

ABSTRACT:

Background

Urolithiasis is a prevalent urological ailment characterized by increasing prevalence and recurrence rates, resulting in substantial social and economic burden. While men exhibit an incidence rate nearly twice that of women, this gender disparity is gradually diminishing. Nevertheless, the mechanisms underlying this condition remain incompletely elucidated. The identification of the urinary microbiome (urobiome) has provided a fresh perspective on urolithiasis. This study aimed to analyze the urobiome of unilateral stone formers in the renal pelvis and evaluate the variations in microbial diversity and community composition between males and females.

Methods

Renal pelvis urine samples were obtained from a cohort of 21 male and 9 female patients and subsequently su

SUBMITTER: Hong SY 

PROVIDER: S-EPMC11539328 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature