Evaluation of the geometric and dosimetric accuracies of deformable image registration of targets and critical organs in prostate CBCT-guided adaptive radiotherapy.

ABSTRACT:

Purpose

Kilovoltage cone beam computed tomography (kVCBCT)-guided adaptive radiation therapy (ART) uses daily deformed CT (dCT), which is generated automatically through deformable registration methods. These registration methods may perform poorly in reproducing volumes of the target organ, rectum, and bladder during treatment. We analyzed the registration errors between the daily kVCBCTs and corresponding dCTs for these organs using the default optical flow algorithm and two registration procedures. We validated the effectiveness of these registration methods in replicating the geometry for dose calculation on kVCBCT for ART.

Methods

We evaluated three deformable image registration (DIR) methods to assess their registration accuracy and dose calculation effeciency in mappi

SUBMITTER: Jassim HH 

PROVIDER: S-EPMC11540054 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature