Adverse health outcomes in offspring of parents with alcohol-related liver disease: Nationwide Danish cohort study.

ABSTRACT:

Background

Parental drinking can cause harm to the offspring. A parent's diagnosis of alcohol-related liver disease (ALD) might be an opportunity to reach offspring with preventive interventions. We investigated offspring risk of adverse health outcomes throughout life, their association with their parent's educational level and diagnosis of ALD.

Methods and findings

We used nationwide health registries to identify offspring of parents diagnosed with ALD in Denmark 1996 to 2018 and age- and sex-matched comparators (20:1). We estimated the incidence rate ratios (IRRs) of hospital contacts with adverse health outcomes, overall and in socioeconomic strata. We used a self-controlled design to examine whether health outcomes were more likely to occur during the first year after t

SUBMITTER: Jepsen P 

PROVIDER: S-EPMC11540217 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature