Local adaptation can cause both peaks and troughs in nucleotide diversity within populations.

ABSTRACT: The amount of standing variation present within populations is a fundamental quantity of interest in population genetics, commonly represented by calculating the average number of differences between pairs of nucleotide sequences (nucleotide diversity, π). It is well understood that both background and positive selection can cause reductions in nucleotide diversity, but less clear how local adaptation affects it. Depending on the assumptions and parameters, some theoretical studies have emphasized how local adaptation can reduce nucleotide diversity, while others have shown that it can increase it. Here, we explore how local adaptation shapes genome-wide patterns in within-population nucleotide diversity, extending previous work to study the effects of polygenic adaptation, genotypic redun

SUBMITTER: Jasper RJ 

PROVIDER: S-EPMC11540321 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature