A role for the circadian photoreceptor CRYPTOCHROME in regulating triglyceride metabolism in Drosophila.

ABSTRACT: The biological rhythms generated by the endogenous circadian clocks across the tree of life regulate numerous behavioral, metabolic, and physiological processes. Although evidence from various studies in Drosophila melanogaster indicates the importance of the core circadian clock genes in the intricate interplay between the circadian clock and metabolism, little is known about the contribution of the circadian photoreceptor/s in this process. The deep brain circadian photoreceptor CRYPTOCHROME (CRY) is essential for resetting the clock in response to light and is also highly expressed in metabolically active tissues in Drosophila. In this study, we sought to explore the possible roles played by CRY in triglyceride (TG) metabolism. We observed that the cry mutant (cry01) flies exhibited inc

SUBMITTER: Gopalakrishnan S 

PROVIDER: S-EPMC11540332 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature