Premorbid frailty, stress hyperglycemia ratio, and functional outcome in patients with acute ischemic stroke.

ABSTRACT:

Background

Frailty, defined as multidimensional prognostic index (MPI), has been recently identified as strong predictor of disability and mortality in the elderly with acute ischemic stroke (AIS). The stress hyperglycemia ratio (SHR) is a recently introduced biomarker significantly associated with poor outcome in AIS.

Objectives

This study aimed to investigate in what extent frailty, measured by MPI, and SHR affects the 3-months outcome of patients > 65 years-old with AIS.

Methods

Consecutive patients with AIS >65 years-old who underwent intravenous thrombolysis (IVT) from 2015 to 2019 were enrolled in a German and an Italian Stroke Unit. The SHR was calculated by dividing the fasting plasma glucose at admission with glycated hemoglobin. Demographics and clinical pre

SUBMITTER: Zedde M 

PROVIDER: S-EPMC11540662 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature