Neural Correlates of Metacognition Impairment in Opioid Addiction.

ABSTRACT:

Background

Individuals with substance use disorder show impaired self-awareness of ongoing behavior. This deficit suggests problems with metacognition, which has been operationalized in the cognitive neuroscience literature as the ability to monitor and evaluate the success of one's own cognition and behavior. However, the neural mechanisms of metacognition have not been characterized in a population with drug addiction.

Methods

Community samples of participants with opioid use disorder (OUD) (n = 27) and healthy control participants (n = 29) performed a previously validated functional magnetic resonance imaging metacognition task (perceptual decision-making task along with confidence ratings of performance). Measures of recent drug use and addiction severity were also acqui

SUBMITTER: Moeller SJ 

PROVIDER: S-EPMC11540741 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature