The oral-gut microbiota relationship in healthy humans: identifying shared bacteria between environments and age groups.

ABSTRACT:

Introduction

Although the oral cavity and the gut are anatomically continuous regions of the gastrointestinal tract, research on the relationship between oral and gut microbiota remains sparse. Oral-gut bacterial translocation is mostly studied in pathological contexts, thus evidence of translocation in healthy conditions is still scarce. Studying the oral-gut microbiota relationship in humans in different life stages is necessary in order to understand how these microbial communities might relate throughout life.

Methods

In this study, saliva and fecal samples were collected from healthy participants (39 children, 97 adults). Microbiota analysis was carried out by sequencing the V4 region of the 16S ribosomal RNA gene, followed by amplicon sequence variant (ASV) analysis.

SUBMITTER: Costa CFFA 

PROVIDER: S-EPMC11540997 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature