Immunisation of the somatostatin gene alters hypothalamic-pituitary-liver gene expressions and enhances growth in Dazu black goats.

ABSTRACT:

Objective

Somatostatin (SS) plays important regulatory roles in animal growth and reproduction by affecting the synthesis and secretion of growth hormone (GH). However, the mechanism by which SS regulates growth and development in goats is still unclear.

Methods

In this study, we randomly selected eight 7-month-old Dazu black goats (DBGs) of similar body weight and equally assigned four bucks as the immunised and negative control groups. The immunised group received the Salmonella typhi attenuated vaccine X9241 (ptCS/2SS-asd) orally, whilst the negative control group received the empty vector vaccine X9241 (pVAX-asd) orally.

Results

The SS concentration in the serum of goats in the immunised group was significantly lower than that in the negative control group, and th

SUBMITTER: Qin G 

PROVIDER: S-EPMC11541029 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature