Detailed lipid investigation of edible seaweeds by photochemical derivatization and untargeted lipidomics.

ABSTRACT: Seaweeds are macrophytic algae that have been gaining interest as alternative healthy foods, renewable drug sources, and climate change mitigation agents. In terms of their nutritional value, seaweeds are renowned for their high content of biologically active polyunsaturated fatty acids. However, little is known about the regiochemistry-the geometry and position of carbon-carbon double bonds-of free and conjugated fatty acids in seaweeds. In the present work, a detailed characterization of the seaweed lipidome was achieved based on untargeted HRMS-based analysis and lipid derivatization with a photochemical aza-Paternò-Büchi reaction. A triple-data processing strategy was carried out to achieve high structural detail on the seaweed lipidome, i.e., (i) a first data processing workflow with

SUBMITTER: Montone CM 

PROVIDER: S-EPMC11541411 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature