Structural and Solution Speciation Studies on fac-Tricarbonylrhenium(I) Complexes of 2,2'-Bipyridine Analogues.

ABSTRACT: In this study, we report the synthesis and characterization of 12 novel rhenium(I) complexes with the general formula fac-[Re(CO)₃(NN)X]ⁿ⁺ where (NN) is a 2,2'-bipyridine analogue ligand, X = Cl^-, Br^-, or H₂O, and n = 0 or 1, focusing on their speciation in an aqueous solution. The prepared organorhenium complexes are stable in a wide pH range in an aqueous solution, and no release of the bidentate ligands or the carbonyl ligands was observed. The stability of the complexes in various biologically relevant matrices (cell culture medium and real blood serum) was also demonstrated. However, the simultaneous substitution of the halido ligand by water and slow hydrolysis of the ester bonds in the ligands were observed, affect

SUBMITTER: Pivarcsik T 

PROVIDER: S-EPMC11541514 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature