Pregnancy during COVID 19 pandemic associated with differential gut microbiome composition as compared to pre-pandemic.

ABSTRACT: The first two years of the COVID-19 pandemic and subsequent health mandates resulted in significant disruptions to daily life, creating a period of heightened psychosocial stress in myriad aspects. Understanding the impact of this period on pregnant individuals' bacteriomes is crucial as pregnancy is a period of heightened vulnerability to stress and its sequelae, anxiety and mood disorders, which have been demonstrated to alter gut microbiome composition. In a prospective cohort study (N = 12-26) conducted from February 2019 to August 2021, we examined psychometric responses and rectal microbiome swabs from pregnant individuals. Full-length 16 S rRNA sequencing followed by calculation of diversity metrics and relative abundance values were used to interrogate fecal microbiome community co

SUBMITTER: Rajasekera TA 

PROVIDER: S-EPMC11541556 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature