The association between early hypotension and neurologic outcome after pediatric cardiac ECPR in children with cardiac disease.

ABSTRACT:

Objective

Explore the relationship between early hypotension after ECPR and survival to hospital discharge (SHD) with favorable neurologic outcome (FNO) in children with cardiac disease.

Methods

Retrospective cohort study of patients undergoing ECPR at a single center pediatric cardiac intensive care unit. Hypotension was defined as MAP < 5th percentile for age. Primary and secondary exposure variables were presence and burden of hypotension respectively, during the first 6 h after ECPR. Our primary outcome was SHD with FNO defined by Pediatric Cerebral Performance Category score of 1-3 or no change from baseline. Secondary outcomes included acute central nervous system (CNS) injury via neuroimaging and EEG. Univariate and multivariable logistic regression analyses were perf

SUBMITTER: Yu P 

PROVIDER: S-EPMC11541672 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature