Psychosis Spectrum Symptoms Before and After Adolescent Cannabis Use Initiation.

ABSTRACT:

Importance

Adolescent cannabis use has been consistently posited to contribute to the onset and progression of psychosis. However, alternative causal models may account for observed associations between cannabis use and psychosis risk, including shared vulnerability for both cannabis use and psychosis or efforts to self-medicate distress from psychosis spectrum symptomology.

Objective

To test 3 hypotheses that may explain cannabis-psychosis risk associations by modeling psychosis spectrum symptom trajectories prior to and after cannabis initiation across adolescent development (approximately 10-15 years of age).

Design, setting, and participants

This cohort study used data from 5 waves across 4 years of follow-up from the Adolescent Brain Cognitive Development (ABCD)

SUBMITTER: Osborne KJ 

PROVIDER: S-EPMC11541740 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature