High incidence of multidrug-resistant tuberculosis in Bhutan: A cohort study based on national TB surveillance data.

ABSTRACT:

Objectives

The emergence of multidrug-resistant tuberculosis (MDR-TB) has made the elimination of TB difficult. Currently, there are limited data on MDR-TB and other drug-resistant TB in Bhutan. We aimed to estimate the incidence and explore the potential risk factors associated with MDR/pre-extensively drug-resistant (pre-XDR)-TB using comprehensive national TB data.

Methods

We used the data from the Tuberculosis Information Surveillance System of the National Tuberculosis Reference Laboratory to analyze the resistance pattern and epidemiologic data for all TB cases tested for resistance for the year 2018-2021. Multiple logistic regression was performed to identify risk factors associated with MDR/pre-XDR-TB.

Results

Of the 2,290 samples tested for drug resistance, 1

SUBMITTER: Dorji T 

PROVIDER: S-EPMC11541819 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature