Use of transportability methods for real-world evidence generation: a review of current applications.

ABSTRACT: Aim: To evaluate how transportability methods are currently used for real-world evidence (RWE) generation to inform good practices and support adoption and acceptance of these methods in the RWE context. Methods: We conducted a targeted literature review to identify studies that transported an effect estimate of the clinical effectiveness or safety of a biomedical exposure to a target real-world population. Records were identified from PubMed-indexed articles published any time before 25 July 2023 (inclusive). Two reviewers screened abstracts/titles and reviewed the full text of candidate studies to identify the final set of articles. Data on the therapeutic area, exposure(s), outcome(s), original and target populations and details of the transportability analysis (e.g., anal

SUBMITTER: Levy NS 

PROVIDER: S-EPMC11542082 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature