Destroyed bladders: Characterization of progressive inflammatory cystitis.

ABSTRACT:

Purpose

We identified a subset of patients with noninfectious cystitis who develop refractory symptoms marked by diffuse inflammatory changes, reduced bladder capacity, and vesicoureteral reflux (VUR), termed here as "progressive inflammatory cystitis" (PIC). Our objective was to describe the phenotype, disease outcomes, and pathologic findings of PIC.

Material and methods

A single institution retrospective cohort study of patients with PIC. Patients with a history of pelvic radiation, urologic malignancy, or neurogenic bladder were excluded. We describe cohort characteristics and use bivariate analyses to compare subgroups. Kaplan-Meier methods estimate time to urinary diversion.

Results

From 2008 to 2020, 46 patients with PIC were identified. The median age of sympt

SUBMITTER: Faris A 

PROVIDER: S-EPMC11542153 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature