Accurate prediction of the lymph node status in ampullary duodenal carcinoma: potential guidance for clinical management.

ABSTRACT:

Purpose

This study aimed to identify the risk factors associated with ampullary duodenal carcinoma (a-DC) and develop a clinical model to dynamically and accurately predict the risk of lymph node metastasis (LNM) in a-DC patients.

Methods

Data from 4077 patients (2004-2020) were extracted from the Surveillance, Epidemiology, and End Results database to form a training cohort, while 173 cases (2010-2020) from Zhejiang Provincial People's Hospital in China were used as an external validation cohort. A reliable LASSO-logistic method was employed to identify independent risk factors for a-DC LNM, and a nomogram was developed based on these factors to assess the risk of a-DC LNM. The nomogram was evaluated using the Akaike information criterion, misclassification error, area unde

SUBMITTER: Ni R 

PROVIDER: S-EPMC11542209 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature