Molecular cloning of PRD-like homeobox genes expressed in bovine oocytes and early IVF embryos.

ABSTRACT:

Background

Embryonic genome activation (EGA) is a critical step in early embryonic development, as it marks the transition from relying on maternal factors to the initiation of transcription from embryo's own genome. The factors associated with EGA are not well understood and need further investigation. PRD-like (PRDL) homeodomain transcription factors (TFs) are considered to play crucial roles in this early event during development but these TFs have evolved differently, even within mammalian lineages. Different numbers of PRDL TFs have been predicted in bovine (Bos taurus); however, their divergent evolution requires species-specific confirmation and functional investigations.

Results

In this study, we conducted molecular cloning of mRNAs for the PRDL TFs ARGFX, DUXA, LEUT

SUBMITTER: Yasar B 

PROVIDER: S-EPMC11542365 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature