Dose delivery uncertainties assessment in the field junction region of craniospinal irradiation with Volumetric Modulated Arc Therapy using a robustness index and experimental dose verification.

ABSTRACT: Due to its inherent technical challenges, craniospinal irradiation (CSI) entails crucial considerations regarding plan complexity and robustness. The scope of this work was to establish and validate methods suitable for the evaluation of robustness, as well as for dose verification in CSI with VMAT. Five patients previously treated with CSI were retrospectively selected. For each patient, two technically different treatment plans were generated, based on the conventional (static overlap) and staggered (dynamic overlap) configuration. These techniques served as a benchmark to evaluate the potential of a metric proposed in this work, aimed at quantifying robustness, the Overlap Robustness Index (ORI). Furthermore, they were utilized to assess the suitability of two experimental methods relyi

SUBMITTER: Peppa V 

PROVIDER: S-EPMC11542795 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature