Pancreatic Cancer: An Exocrine Tumor With Endocrine Characteristics.

ABSTRACT:

Objective

To examine the characteristics of patients with pancreatic cancer with long-term survival.

Background

Although pancreatic cancer is a highly lethal malignancy, a minority of patients experience long-term survival. The characteristics of these patients remain largely unidentified.

Methods

An indolent subgroup was established using carbohydrate antigen 19-9 (CA19-9), which is the best-validated biomarker for pancreatic cancer. Of 1558 patients, 13.9% were included in the CA19-9-normal (≤37 U/mL) subgroup.

Results

A normal CA19-9 level was an independent variable for overall survival (median survival, 18.1 vs 9.7 months, hazard ratio = 0.53, P < 0.001). The 5-year survival of patients with stage IV CA19-9-normal cancer was higher than that of patients wi

SUBMITTER: Zhu X 

PROVIDER: S-EPMC11542970 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature