Krukenberg tumours: which patients should be considered for surgery?-a narrative literature review.

ABSTRACT:

Background and objective

Krukenberg tumours (KTs) are metastatic signet ring cell (SRC) adenocarcinomas of the ovary, arising from the stomach in most cases (70%). Other common primary sites are the colon, appendix and breast. The use of the term "Krukenberg tumour" is inconsistent in the literature which makes data interpretation difficult. Prognosis of KTs is dismal and, in the absence of randomised controlled trials, the best treatment strategies remain controversial. Evidence from retrospective studies suggests that metastectomy is associated with improved survival. Our narrative literature review set out to determine which patients gain maximal survival benefit from surgical management.

Methods

A comprehensive literature search was performed using PubMed and Google Scho

SUBMITTER: Nistor SI 

PROVIDER: S-EPMC11543025 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature