Up-regulation of MSMO1 was associated with poor survival in cervical cancer.

ABSTRACT:

Background

Methylsterol monooxygenase 1 (MSMO1) catalyzes C4-methylsterols demethylation in cholesterol biosynthesis pathway. MSMO1 is increased and up-regulation of MSMO1 is correlated with progression of some tumor. But the correlation of MSMO1 to cervical cancer is unknown. The current study aimed to explore the expression pattern of MSMO1 in cervical cancer and its correlation to clinical characteristics.

Methods

In this study, 306 cervical cancer cases and 13 non-tumor cases were included. We compared MSMO1 expression level in non-tumor cervical tissues and cervical cancer samples using the Wilcoxon rank sum test. Univariate regression was used to investigate the correlation between MSMO1 expression as well as other clinical characteristics and prognosis. Clinical chara

SUBMITTER: Zou J 

PROVIDER: S-EPMC11543037 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature