Pain and small fiber pathology in men with fibromyalgia syndrome.

ABSTRACT:

Introduction

Small fiber pathology may be involved in the pathophysiology of pain in women with fibromyalgia syndrome (FMS).

Objectives

This prospective single-center case-control study provides detailed pain phenotyping and small fiber pathology data in a cohort of men with FMS on a morphological and functional level.

Methods

Forty-two men with FMS underwent a comprehensive pain-related interview and neurological examination, a questionnaire and neurophysiological assessment, and specialized small fiber tests: skin punch biopsy, quantitative sensory testing including C-tactile afferents, and corneal confocal microscopy. Data were compared with those of healthy male controls.

Results

Men with FMS reported generalized and permanent pain with additional pain atta

SUBMITTER: Feulner B 

PROVIDER: S-EPMC11543218 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature