Prognostic values of tumor size and location in early stage endometrial cancer patients who received radiotherapy.

ABSTRACT:

Objective

To investigate the correlation between tumor size, tumor location, and prognosis in patients with early-stage endometrial cancer (EC) receiving adjuvant radiotherapy.

Methods

Data of patients who had been treated for stage I-II EC from March 1999 to September 2017 in 13 tertiary hospitals in China was screened. Cox regression analysis was performed to investigate associations between tumor size, tumor location, and other clinical or pathological factors with cancer-specific survival (CSS) and distant metastasis failure-free survival (DMFS). The relationship between tumor size as a continuous variable and prognosis was demonstrated by restricted cubic splines. Prognostic models were constructed as nomograms and evaluated by Harrell's C-index, calibration curves and

SUBMITTER: Jiao S 

PROVIDER: S-EPMC11543252 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature