Impact of persistent PSA after salvage radical prostatectomy: a multicenter study.

ABSTRACT:

Background and objective

Persistent prostatic specific antigen (PSA) represents a poor prognostic factor for recurrence after radical prostatectomy (RP). However, the impact of persistent PSA on oncologic outcomes in patients undergoing salvage RP is unknown. To investigate the impact of persistent PSA after salvage RP on long-term oncologic outcomes.

Material and methods

Patients who underwent salvage RP for recurrent prostate cancer between 2000 and 2021 were identified from twelve high-volume centers. Only patients with available PSA after salvage RP were included. Kaplan-Meier analyses and multivariable Cox regression models were used to test the effect of persistent PSA on biochemical recurrence (BCR), metastasis and any death after salvage RP. Persistent PSA was define

SUBMITTER: Preisser F 

PROVIDER: S-EPMC11543598 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature