Association between soy products and prostate cancer: A systematic review and meta-analysis of observational studies.

ABSTRACT:

Purpose

The effect of soy products on prostate cancer (PCA) remains a topic of debate. This study aimed to investigate the association between soy products consumption and the incidence of PCA.

Materials and methods

A search was conducted in the PubMed, EBSCO, Web of Science, and Cochrane Library databases up to December 2023. The adjusted odds ratio (OR) and corresponding 95% confidence interval (CI) were used to assess the association.

Results

A total of 22 articles, comprising 1,409,213 participants, were included for this meta-analysis. The results indicate that soy products reduce the risk of PCA (OR=0.94, 95% CI=0.91-0.97, p<0.001), especially in cases of localized or low-grade PCA (OR=0.94, 95% CI=0.90-0.97, p<0.001), but exhibit no effect on non-localized or h

SUBMITTER: Huang Y 

PROVIDER: S-EPMC11543648 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature