Topical fluoride varnish application shifts dysbiotic dental plaque microbiome towards eubiosis in children with dental caries.

ABSTRACT:

Objective

This study used high-throughput amplicon sequencing to examine the impact of long-term continuous fluoride treatment on the dental plaque microbiota of children aged 8 to 9 with mixed dentition.

Design

The study population consisted of twenty 8-9-year-old children with dental caries. Topical application of fluoride-varnish was weekly administered for one month to all subjects. Clinical indicators and anthropological data, such as the caries index (DMFT and dmft), were documented for every participant at baseline. A baseline assessment and a month after the fluoride varnish treatment were conducted for the salivary pH level and the Patient-Hygiene-Performance (PHP) index. Following application of the fluoride varnish, plaque samples were obtained both one month late

SUBMITTER: Sari Widyarman A 

PROVIDER: S-EPMC11544270 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature