Linking the microarchitecture of neurotransmitter systems to large-scale MEG resting state networks.

ABSTRACT: Neuronal oscillations are ubiquitous in brain activity at all scales and their synchronization dynamics are essential for information processing in neuronal systems. The underlying synaptic mechanisms, while mainly based on GABA- and glutamatergic neurotransmission, are influenced by neuromodulatory systems that have highly variable densities of neurotransmitter receptors and transporters across the cortical mantle. How they constrain the network structures of interacting oscillations has remained a central unaddressed question. We asked here whether the receptor and transporter densities covary with the frequency-specific neuroanatomical patterns of inter-areal phase synchrony (PS) and amplitude correlation (AC) networks in resting-state magnetoencephalography (MEG) data. Network centrali

SUBMITTER: Siebenhuhner F 

PROVIDER: S-EPMC11544385 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature