Childhood Community Disadvantage and MRI-Derived Structural Brain Integrity After Age 65 Years.

ABSTRACT:

Importance

Prior studies associate late-life community disadvantage with worse brain health. It is relatively unknown if childhood community disadvantage associates with late-life brain health.

Objective

To test associations between childhood residence in an economically disadvantaged community, individual income and education, and late-life cortical brain volumes and white matter integrity.

Design, setting, and participants

This cohort study was conducted in the ongoing harmonized cohorts KHANDLE (Kaiser Healthy Aging and Diverse Life Experiences Study; initiated 2017) and STAR (Study of Healthy Aging in African Americans; initiated 2018) using all available data collected out of a regional integrated health care delivery network in California between cohort initiati

SUBMITTER: Peterson RL 

PROVIDER: S-EPMC11544493 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature