Performance of Risk Models for Antimicrobial Resistance in Adult Patients With Sepsis.

ABSTRACT:

Importance

The results of prediction models that stratify patients with sepsis and risk of resistant gram-negative bacilli (GNB) infections inform treatment guidelines. However, these models do not extrapolate well across hospitals.

Objective

To assess whether patient case mix and local prevalence rates of resistance contributed to the variable performance of a general risk stratification GNB sepsis model for community-onset and hospital-onset sepsis across hospitals.

Design, setting, and participants

This was a retrospective cohort study conducted from January 2016 and October 2021. Adult patients with sepsis at 10 acute-care hospitals in rural and urban areas across Missouri and Illinois were included. Inclusion criteria were blood cultures indicating sepsis, having

SUBMITTER: Vazquez Guillamet MC 

PROVIDER: S-EPMC11544496 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature