Age and Late Recurrence in Young Patients With ER-Positive, ERBB2-Negative Breast Cancer.

ABSTRACT:

Importance

Young patients with breast cancer with estrogen receptor (ER)-positive, ERBB2-negative tumors have a poor prognosis. Understanding factors influencing late recurrence is crucial for improving management and outcomes.

Objective

To determine whether age is an independent factor associated with late distant recurrence (DR) in young patients with ER-positive, ERBB2-negative cancers without distant metastasis within 5 years from surgery.

Design, setting, and participants

This multicenter retrospective cohort study analyzed clinical records of patients with breast cancer who underwent surgery from January 2000 to December 2011 with at least 5 years of follow-up. The study was conducted at Samsung Medical Center, Gangnam Severance Hospital, and Seoul National Univ

SUBMITTER: Shin DS 

PROVIDER: S-EPMC11544499 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature