Electrocatalytic Hydrogenation of Pyridines and Other Nitrogen-Containing Aromatic Compounds.

ABSTRACT: The production of cyclic amines, which are vital to the pharmaceutical industry, relies on energy-intensive thermochemical hydrogenation. Herein, we demonstrate the electrocatalytic hydrogenation of nitrogen-containing aromatic compounds, specifically pyridine, at ambient temperature and pressure via a membrane electrode assembly with an anion-exchange membrane. We synthesized piperidine using a carbon-supported rhodium catalyst, achieving a current density of 25 mA cm^-2 and a current efficiency of 99% under a circular flow until 5 F mol^-1. Quantitative conversion of pyridine into piperidine with 98% yield was observed after passing 9 F mol^-1, corresponding to 65% of current efficiency. The reduction of Rh oxides on the catalyst surface was crucial for cata

SUBMITTER: Shida N 

PROVIDER: S-EPMC11544711 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature