Circular RNA as Diagnostic and Prognostic Biomarkers in Hematological Malignancies:Systematic Review.

ABSTRACT: Objectives: While various serum and tissue biomarkers have been explored for tumor diagnosis, the sensitivity and specificity have not yield optimal results. Circular RNAs (circRNAs) are more stable, conserved, and tissue-specific than linear RNA. Recent reports indicate that circRNAs could serve as potential biomarkers in the diagnosis or/and prognosis of tumors. In this study, we systematically examined the relationship between circRNA expression and diagnostic and prognostic outcomes in patients with hematological tumors. Methods: We searched several databases, including Google Scholar, MEDLINE, Scopus, PubMed, Embase, ScienceDirect, Ovid-Medline, Chinese National Knowledge Infrastructure, WanFang and SinoMed, with a cutoff date of June 12, 2024. The study protocol was PRO

SUBMITTER: Gao L 

PROVIDER: S-EPMC11544746 | biostudies-literature | 2024 Jan-Dec

REPOSITORIES: biostudies-literature