Impact of General Anesthesia on Ciliary Functional Analysis by Digital High-Speed Videomicroscopy in Suspected Primary Ciliary Dyskinesia.

ABSTRACT: Digital high-speed videomicroscopy (DHSV) is a crucial tool for evaluating ciliary function in children suspected of primary ciliary dyskinesia (PCD). However, until now, samples are taken without anesthesia due to uncertainty about its effect on ciliary function and DHSV interpretation. This study aimed to investigate the impact of general anesthesia on ciliary functional analysis by DHSV in a series of three patients listed for ENT surgeries, which could improve diagnostic procedures for pediatric patients. Patient 1 (7-year-old girl) underwent adenotonsillectomy and tympanostomy placement tube, while patients 2 (17-month-old boy) and 3 (15-month-old girl) underwent adenoidectomy and tympanostomy placement tube. All patients underwent nasal brushing before general anesthesia (control sam

SUBMITTER: Benchimol L 

PROVIDER: S-EPMC11544925 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature