Assessment of Microcirculatory Dysfunction by Measuring Subcutaneous Tissue Oxygen Saturation Using Near-Infrared Spectroscopy in Patients with Circulatory Failure.

ABSTRACT:

Background

Patients with circulatory failure have high mortality rates and require prompt assessment of microcirculation. Despite the improvement in hemodynamic parameters, microcirculatory dysfunction persists. We measured subcutaneous regional tissue oxygen saturation (rSO₂) with near-infrared spectroscopy (NIRS), which can assess microcirculation in patients with circulatory failure.

Methods

A finger-worn oximeter with NIRS measured rSO₂ in the forehead, thenar eminence, thumb, and knees. First, the rSO₂ was measured in healthy adult volunteers (n = 10). Circulatory failure was defined as a systolic blood pressure ≤ 90 mmHg and lactate ≥ 2 mmol/L. The study included 35 patients without circulatory failure and SOFA score of 0 at ICU

SUBMITTER: Sato J 

PROVIDER: S-EPMC11545383 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature