Association Between Chemotherapy-Induced Peripheral Neuropathy and Low Anterior Resection Syndrome.

ABSTRACT:

Introduction

Low anterior resection syndrome (LARS) can be a debilitating condition that develops after undergoing sphincter-preserving surgery for rectal cancer. Chemotherapy-induced peripheral neuropathy is a common side effect of platinum-based chemotherapy agents used as systemic therapy for rectal cancer treatment. The purpose of this study was to determine the potential relationship between CIPN and LARS.

Methods

This was a retrospective review of patients who underwent a low anterior resection for rectal cancer and received systemic therapy contacted at least six months from the most recent surgery. Eligible patients were called and completed the relevant surveys over the phone or email.

Results

There was a total of 42 patients who completed the surveys with 33

SUBMITTER: Linhares SM 

PROVIDER: S-EPMC11545659 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature