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The Impact of Gestational Diabetes Mellitus on Minipuberty in Girls.


ABSTRACT: Minipuberty is the second phase of physiological activation of the reproductive axis, playing a role in the postnatal development of sexual organs. The course of female minipuberty was found to be affected by low maternal vitamin D status and hypothyroidism during pregnancy. The aim of the current study was to assess the hormonal profile and the size of sexual organs in daughters of mothers with gestational diabetes mellitus. The study included three matched groups of infant girls: daughters of healthy women without metabolic disorders during pregnancy (group 1), daughters of women with poorly controlled gestational diabetes mellitus (group 2), and daughters of women with gestational diabetes mellitus adequately controlled during pregnancy (group 3). Urinary levels of gonadotropins, saliva

SUBMITTER: Kowalcze K 

PROVIDER: S-EPMC11545881 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature