Global changes in the pattern of connectivity in developmental prosopagnosia.

ABSTRACT: Developmental prosopagnosia is a neurodevelopmental condition characterized by difficulties in recognizing the identity of a person from their face. While current theories of the neural basis of developmental prosopagnosia focus on the face processing network, successful recognition of face identities requires broader integration of neural signals across the whole brain. Here, we asked whether disruptions in global functional and structural connectivity contribute to the face recognition difficulties observed in developmental prosopagnosia. We found that the left temporal pole was less functionally connected to the rest of the brain in developmental prosopagnosia. This was driven by weaker contralateral connections to the middle and inferior temporal gyri, as well as to the medial prefront

SUBMITTER: Epihova G 

PROVIDER: S-EPMC11546179 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature